Insights into SARS-CoV-2 infection and recovery trajectories.

A longitudinal cohort study in Switzerland found that up to 18% of unvaccinated individuals who had a confirmed SARS-CoV-2 infection experienced post-covid-19 condition up to two years after infection, with evidence of excess symptom risk compared with controls. The study also found that most participants had continued recovery or overall improvement in health status over time, but 5.2% had a worsening in health status and 4.4% had alternating periods of recovery and health impairment. Effective interventions are needed to reduce the burden of post-covid-19 condition.