Research Links Older Fathers to Increased Harmful Mutations in Offspring
TL;DR Summary
The article discusses research on human mutation hotspots indicating clonal expansions in spermatogonia, highlighting the role of positive selection and mutation processes in the male germline and their implications for human genetic diversity and disease.
Topics:health#clonal-expansion#genetic-variation#germline-mutations#human-mutation#science#spermatogonia
- Hotspots of human mutation point to clonal expansions in spermatogonia Nature
- Sperm sequencing reveals extensive positive selection in the male germline Nature
- Selfish sperm see older fathers pass on more disease-causing mutations New Scientist
- Study Finds Positive Selection Shapes Genetic Mutations in Male Germline Through Sperm Analysis geneonline.com
- Why Older Fathers Pass on More Harmful Mutations to Their Kids Neuroscience News
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