"Gene silencing enzyme shows promise in targeting HIV infection"

Researchers from the University of California, Irvine have developed a DNA enzyme that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. The Dz 46 enzyme specifically targets the allele-specific RNA mutation in the KRAS gene, found in 25 percent of all human cancers. This breakthrough "gene silencing" technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases, and neurological disorders, offering patients an innovative, precision medicine treatment.