"Moderate Acetaminophen Use Linked to Heart Function Changes"

A new study conducted in mice suggests that regular use of acetaminophen at moderate doses, considered safe at 500 mg/day, can alter proteins in the heart tissue, potentially leading to heart issues as a result of oxidative stress or toxin buildup. The research, presented at the American Physiology Summit, found that acetaminophen caused significant changes in the levels of proteins associated with various biochemical pathways in the heart. While the study was conducted in mice and may not directly apply to humans, researchers recommend limiting acetaminophen use to a few days at a stretch and discussing concerns about high-dose use with a healthcare provider.