The Challenges of Developing a Dengue Fever Vaccine.

Dengue fever, a mosquito-borne disease, has been on the rise in the last two decades, with half the world's population at risk. While a vaccine has been developed, it has faced safety concerns, and there is no universally available prevention method. However, an initiative to breed virus-resistant mosquitoes using the bacterium Wolbachia has seen success in Australia. Vaccine manufacturers and public health leaders need to learn from past mistakes to ensure faith in interventions does not wane.