Depression linked to disrupted gut microbiome and energy metabolism.

A new study published in JAMA Psychiatry reveals associations between alterations in lipid and energy metabolism, specific types of gut bacteria, and the presence of depressive symptoms, shedding light on the potential role of the gut-brain axis in depression. The study focused on variations in lipids and metabolites associated with major depressive disorder (MDD) and found that the metabolic shifts observed in depression were connected to specific types of gut bacteria. The findings also supported previous studies that had reported similar associations between depression and changes in lipid profiles.