"Christina Applegate's 7-Year Battle with MS Symptoms and Bond with Jamie-Lynn Sigler"

Actress Christina Applegate revealed that she likely experienced multiple sclerosis symptoms for six or seven years before being diagnosed in 2021. She initially dismissed the symptoms, attributing them to fatigue or dehydration, but eventually had to use a wheelchair on set. Applegate credits her Sweetest Thing costar Selma Blair with urging her to get tested for the disease. While she has received support, she admits to feeling angry about her diagnosis and is currently isolating to cope with the challenges of living with multiple sclerosis.