Christina Applegate Opens Up About Severe MS Pain

Christina Applegate has opened up about the severe pain she experiences daily due to multiple sclerosis (MS), describing how it affects her ability to perform simple tasks and her overall quality of life. On her "MeSsy" podcast, she shared that the pain is so intense she often lies in bed "screaming" and struggles with mobility, sometimes needing to use a cane and wear diapers. Diagnosed in 2021, Applegate has been candid about how MS has impacted her health and career, indicating that her role in "Dead to Me" might be her last due to her declining condition.