Christina Applegate Opens Up About MS Pain: 'I Lay in Bed Screaming'

Christina Applegate has shared details about the progression of her multiple sclerosis diagnosis on her podcast, MeSsy, co-hosted with Jamie-Lynn Sigler. Applegate described the severe chronic pain she experiences, which affects her ability to perform daily tasks like picking up her phone or opening bottles. She highlighted the invisible nature of the disease, which was echoed by their guest, Rory Kandel, who also suffers from MS. The condition, affecting nearly a million people in the U.S., is characterized by its unpredictable impact on the nervous system.