Tag

Vascular Complications

All articles tagged with #vascular complications

health5 hours ago•10 min saved

Impella Unloading Fails to Reduce Infarct Size in Anterior STEMI Without Shock

The STEMI Door-to-Unload (DTU) trial found that unloading the left ventricle with Impella CP 30 minutes before PCI in patients with anterior STEMI without cardiogenic shock did not reduce infarct size compared with PCI alone. Importantly, the Impella strategy delayed reperfusion (about 40 minutes to PCI and ~47 minutes total ischemic time) and increased major bleeding (≈30%) and vascular complications, with no improvement in secondary outcomes. The study concludes Impella is not recommended for infarct-size reduction in this population, though it remains relevant for cardiogenic shock; future research may explore alternative strategies.

via tctmd.com|

#dtu-trial #health #impella

health2 years ago•4 min saved

The Long-Term Consequences of Type 2 Diabetes in Children

Children with type 2 diabetes face a high incidence of vascular complications as they age into young adulthood, with an 80% incidence of at least one complication during up to 15 years of follow-up. Arterial stiffness and worsened cardiac function often appear in these children within 2-5 years of diagnosis and seem driven in part by the development of hypertension and worsening A1c levels. The dire prognosis is a reason to aggressively treat these patients with antidiabetic medications from drug classes with proven cardiovascular disease protection, specifically sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) agonists.

via Medscape|

#a1c #antidiabetic-medications #cardiovascular-disease