"Early PCI Shows Promise in Reducing Risks of Vulnerable Coronary Plaques"
The PREVENT trial of preventive coronary stents targeting vulnerable plaques showed promising results at the American College of Cardiology meeting, with an 89% reduction in major cardiac events at 2 years. However, concerns about the small number of events, overestimation of outcome rates, open-label design, and limited clinical translation suggest caution in interpreting the results. While the study provides hope in understanding vulnerable plaques, it's too early to change current PCI practice, and further studies are needed to validate these findings.