The Link Between Allergies, Sinus Pressure, and Headaches
A reader asks Dr. Keith Roach about histamine intolerance and its connection to high-histamine foods. Dr. Roach explains that there is no evidence of a deficiency in the enzymes that metabolize histamine and that treatment with diamine oxidase (DAO) has not been proven effective. Instead, he suggests trying newer antihistamines like cetirizine or fexofenadine, along with an H2 antihistamine like famotidine. Another approach is using Cromolyn before eating. In another question, Dr. Roach addresses numbness and burning in the outer thigh, which could be a result of nerve compression known as meralgia paresthetica. He recommends avoiding compression, and if necessary, seeking a nerve block or using medications for neuropathic pain.