"Non-Hormonal Male Birth Control: A Promising, Side-Effect-Free Breakthrough"
The Salk Institute has developed a non-hormonal and reversible male contraceptive method using HDAC inhibitors to block sperm production without affecting libido, offering a significant advancement in male birth control. Administering an HDAC inhibitor orally stopped sperm production and fertility in mice without impacting their libido, and the effects were fully reversible. This novel approach targets the regulation of gene expression in sperm production, providing a promising therapeutic approach for human clinical trials.