"Unlocking the Potential: Glutamate Receptor Activation as a Cure for Opioid Addiction"
Scientists have discovered a potential new treatment for opioid use disorder (OUD) by targeting metabotropic glutamate 2 receptors in the brain. The drug ADX106772, produced by Addex Therapeutics, reduces oxycodone intake and drug-seeking behavior in an animal model without affecting other reward responses. OUD affects over two million people in the U.S., with around 70,000 dying from opioid overdoses annually. This research offers hope for developing new therapies to combat opioid addiction and reduce its devastating impact.