"Revolutionary Raman Breakthrough Ends Decades of Frustration"
Researchers at Texas A&M University have developed a new technique called thermostable-Raman-interaction-profiling (TRIP) that overcomes the limitations of Raman spectroscopy in studying live proteins. By cooling the surface or substrate, the proteins remain intact during optical measurements, leading to highly reproducible results. This breakthrough has significant implications for drug and vaccine testing, as well as clinical diagnostics, by shortening the timeline and improving accuracy. The TRIP technique also requires smaller sample sizes and lower protein concentrations, making it a more cost-effective process. Future applications may include DNA analysis and other biological molecules.