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Diclofenac

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health2 years ago

Identifying the Cause of Severe Adverse Reactions in Popular Pain Medication.

Researchers have found that the safety issues surrounding the commonly used pain reliever, diclofenac, may be linked to a poorly understood drug-metabolizing enzyme. The expression of this enzyme can vary as much as 3,000 times from one individual to the next. The findings have the potential to be used for developing methods of identifying individuals who are vulnerable to severe side effects from diclofenac. These methods could also aid in determining safe dosing guidelines for specific demographic groups, including women, young children, and individuals from certain ethnic backgrounds.