Brain 'Reset Wave' Could Explain ECT's Rapid Depression Relief
New research suggests that electroconvulsive therapy (ECT) not only induces seizures but also triggers a brain 'reset' wave called cortical spreading depolarization (CSD), which may explain its rapid and widespread therapeutic effects. Using advanced neuroimaging, scientists aim to personalize ECT treatments by monitoring CSD as a biomarker, potentially improving outcomes for treatment-resistant mental illnesses.