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Coronaviruses

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health2 years ago

New coronaviruses discovered in UK bats with potential to infect humans

A survey of UK bat species has uncovered new coronaviruses, including some from the same group as SARS-CoV-2. Laboratory studies suggest that some share key adaptations with SARS-CoV-2 but are unlikely to spread in humans without further evolution. The researchers created pseudoviruses to gauge the threat posed by the UK coronaviruses and found that one sarbecovirus found in a lesser horseshoe bat had a spike protein that was able to infect human cells by attaching to a protein called ACE2, the same receptor used by SARS-CoV-2. However, the UK sarbecovirus's version of spike didn't attach nearly as strongly as SARS-CoV-2's, making it unlikely that the virus could readily infect people and spread.