Innovative Retainer Delivers Consistent Levodopa Doses
Originally Published 1 year ago — by Parkinson's News Today
A new teeth-retainer system called DopaFuse, developed by SynAgile, can continuously deliver high doses of levodopa and carbidopa to help manage motor symptoms in advanced Parkinson's disease patients. This system, tested in a Phase 2 study, provides more stable medication levels and better symptom control by releasing a paste formulation of the drugs into the mouth, allowing for doses up to 1,200 mg per day without invasive methods.