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Antibody Based Drug

All articles tagged with #antibody based drug

health1 year ago

Nirsevimab: A Breakthrough in RSV Protection for Infants

A new antibody-based drug, nirsevimab, has shown to be 93% effective in preventing hospitalization and 89% effective in reducing doctor visits for RSV in infants, according to a study published in JAMA Pediatrics. Approved in 2023, nirsevimab provides lab-made antibodies to block RSV, offering a significant public health benefit if widely used. Despite its effectiveness, uptake has been low due to supply issues and timing of availability. The drug is recommended for infants under 8 months old, especially if their mothers haven't received the maternal RSV vaccine.

health2 years ago

Antibody-based drug linked to eye inflammation in macular degeneration patients.

Brolucizumab, a monoclonal antibody drug developed by Novartis for macular degeneration, has been linked to rare retinal side effects in some patients due to its interactions with the immune system. The drug was approved in 2019 and is used to target the overgrowth of abnormal blood vessels that cause vision loss in AMD. Scientists at Novartis have conducted two studies to determine why the medication caused retinal disorders in some patients. The studies found that an immune response against brolucizumab was a prerequisite for both side effects, and other factors may also contribute to some patients having retinal vasculitis or retinal vascular occlusion.