Smart Risk Takers Avoid This Mistake, According to Self-Made Millionaire.

John Crowley, executive chairman of Amicus Therapeutics, advises against setting lofty, broad goals of changing the world, as very few people have achieved it. Instead, smart risk-takers should define their mission and focus on clear, tangible goals that address an urgent need. Crowley modeled this approach when he co-founded Novazyme Pharmaceuticals to find a cure for his children's rare neuromuscular disorder. Many successful companies, such as Microsoft and Apple, also started with concise goals. Starting small gives the opportunity to expand once the goal is met.