Mapping Genomic Mutational Constraints and Disease-Related Variants in Human Genomes

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Source: Nature.com
Mapping Genomic Mutational Constraints and Disease-Related Variants in Human Genomes
Photo: Nature.com
TL;DR Summary

The article provides information on the data and code availability for a genomic mutational constraint map using variation in 76,156 human genomes. The aggregated allele frequency dataset is available for download, along with constraint statistics, and individual-level data for specific projects. The code for quality control and computation of constraint statistics is also publicly available. The article includes references to related studies and resources for further exploration.

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