Over-50s Experience Second Midlife Crisis Amid Pandemic

The COVID-19 pandemic triggered a second "midlife crisis" for those aged 50 and older, with women struggling more than men with psychological distress. This may exacerbate and accelerate neurodegeneration, mental health, and overall health disorders. Long-term psychological distress trajectories of adults born between 1946 and 1970 were disrupted during the pandemic, particularly among women, who reached the highest levels ever recorded in up to 40 years of follow-up data. This may impact future trends of morbidity, disability, and mortality due to common mental health problems.