"Groundbreaking Discovery: Reversing Fentanyl's Devastating Effects with a New Method"

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Source: Phys.org
"Groundbreaking Discovery: Reversing Fentanyl's Devastating Effects with a New Method"
Photo: Phys.org
TL;DR Summary

Researchers at Indiana University have discovered a new method to reverse the effects of fentanyl, a synthetic opioid that is significantly stronger than morphine. The study, published in the Journal of Medicinal Chemistry, suggests that cannabidiol (CBD) could act as a negative allosteric modulator at the binding site, effectively reversing the effects of fentanyl. Further testing is needed to determine if this method can reverse respiratory depression, the main overdose effect, in living organisms. This research could potentially lead to the development of a new product or a combination therapy with naloxone to combat fentanyl overdoses.

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