Breakthrough in Targeting Pancreatic Cancer's Genetic Circuit
TL;DR Summary
Researchers have identified a molecular circuit involving SRSF1, AURKA, and MYC that drives aggressive pancreatic cancer. They developed an antisense oligonucleotide that disrupts this circuit, causing cancer cells to die, which could lead to new treatments for pancreatic cancer in the future.
- A hidden loop is powering deadly pancreatic cancer ScienceDaily
- Short-circuiting pancreatic cancer Cold Spring Harbor Laboratory
- Novel antisense oligonucleotide shows promise against aggressive pancreatic cancer News-Medical
- Circuit Driving Aggressive Pancreatic Cancer Targeted by Splice-Switching ASO Inside Precision Medicine
- Pancreatic Cancer’s Three-Gene Circuit Collapses When Scientists Block One Splice ScienceBlog.com
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