FDA approves Rinvoq as first JAK inhibitor for Crohn's Disease.

TL;DR Summary
FDA has approved Rinvoq (upadacitinib) as the first oral treatment for adults with moderately to severely active Crohn’s disease who have had an inadequate response or intolerance to one or more tumor necrosis factor blockers. Rinvoq is a Janus kinase (JAK) inhibitor and should not be used in combination with other JAK inhibitors, biological therapies for Crohn’s disease, or with strong immunosuppressants such as azathioprine and cyclosporine. The most common side effects of Rinvoq are upper respiratory tract infections, anemia, fever, acne, herpes zoster, and headache.
- FDA approves first oral treatment for moderately to severely active Cr FDA.gov
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- AbbVie gains Crohn's disease indication for Rinvoq in US (NYSE:ABBV) Seeking Alpha
- FDA Approves Upadacitinib (Rinvoq) for Crohn's Disease Medscape
- First JAK Inhibitor Approved for Crohn's Disease Medpage Today
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