FDA Approves Multiple New Options for Opioid Use Disorder Treatment and Overdose Reversal

TL;DR Summary
The FDA has approved Brixadi, a new buprenorphine extended-release injection for subcutaneous use, to treat moderate to severe opioid use disorder. Brixadi is available in weekly and monthly formulations and offers a new option for people in recovery who may benefit from a weekly injection to maintain treatment adherence. The most common adverse reactions include injection-site pain, headache, constipation, nausea, injection-site erythema, itchy skin at the injection site, insomnia, and urinary tract infections. The FDA continues to implement a comprehensive approach to increase options to treat OUD.
- FDA Approves New Buprenorphine Treatment Option for Opioid Use Disorder FDA.gov
- A new nasal spray to reverse fentanyl and other opioid overdoses gets FDA approval NPR
- Analysis | A new opioid overdose antidote to enter the market The Washington Post
- Braeburn's BRIXADI™ (buprenorphine) Extended-Release Subcutaneous Injection (CIII) Receives FDA Approval for Moderate to Severe Opioid Use Disorder PR Newswire
- Decision made on RX nasal spray for opioid overdoses WJW FOX 8 News Cleveland
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