Enzymatic DNA Synthesis: The Future of Synthetic Biology
Ansa Biotechnologies, a DNA synthesis startup, has successfully synthesized the world's longest synthetic oligonucleotide using enzymatic DNA synthesis, which leverages a polymerase enzyme called terminal deoxynucleotidyl transferase (TdT). This process produces less waste, boasts higher fidelity, and can produce longer DNA molecules than traditional phosphoramidite chemistry. Ansa's goal is to provide gene-length synthetic DNA directly to customers, removing the need for researchers to think about how they get the DNA to do their experiments.