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Orna Therapeutics

All articles tagged with #orna therapeutics

biotech17 days ago•3 min saved

Lilly bets on in vivo CAR-T with $2.4B Orna Therapeutics deal

Eli Lilly agreed to acquire Orna Therapeutics for up to $2.4 billion to gain an in vivo CAR-T platform using engineered circular RNA delivered by lipid nanoparticles, led by ORN-252 targeting CD19 for autoimmune diseases; terms include upfront and milestone-based payments. The deal follows a wave of pharma acquisitions in this space as Lilly expands its genetic medicines pipeline and Orna has drawn funding and collaborations since its 2021 launch.

via Fierce Biotech|

#biotech #circular-rna #in-vivo-car-t

biotech-healthcare17 days ago•5 min saved

Lilly to Acquire Orna Therapeutics to Accelerate In Vivo CAR-T

Eli Lilly will acquire Orna Therapeutics in a deal worth up to $2.4 billion in cash, expanding Lilly’s genetic-medicine platform with Orna’s circular-RNA–based in vivo CAR-T technology (ORN-252) designed to treat B cell–driven autoimmune diseases, leveraging lipid nanoparticle delivery for potentially more durable therapeutic protein expression and broader in vivo cell-therapy options.

via PR Newswire|

#biotech-healthcare #car-t #circular-rna

business17 days ago•4 min saved

Lilly to acquire Orna, betting on in vivo CAR-T and circular RNA medicines

Eli Lilly will acquire Orna Therapeutics in a deal potentially worth up to $2.4 billion to accelerate in vivo CAR-T therapies using circular RNA and lipid nanoparticle delivery, led by ORN-252 targeting CD19 for B cell–driven autoimmune diseases and offering potentially more durable protein expression than current RNA or ex vivo approaches.

via Eli Lilly|

#business #circular-rna #in-vivo-car-t