
49ers vs. Colts: Key storylines, injury updates, and predictions for Monday Night Football
The Colts, facing a tough 49ers defense on Monday Night Football, will rely on veteran QB Philip Rivers and RB Jonathan Taylor to navigate a game where the 49ers' defense has been weakened by injuries but remains resilient, especially against explosive plays. The game emphasizes methodical offense and strategic play-calling to overcome the 49ers' defensive strengths.













