Tag

Opdivo

All articles tagged with #opdivo

"ESMO Abstract Leak Unveils Exciting NSCLC Therapies and Neoadjuvant Nivolumab Advancements"
medical-oncology2 years ago

"ESMO Abstract Leak Unveils Exciting NSCLC Therapies and Neoadjuvant Nivolumab Advancements"

The European Society for Medical Oncology (ESMO) Congress 2023 has experienced an embargo breach, revealing promising therapies for non-small cell lung cancer (NSCLC). Bristol Myers Squibb's Opdivo demonstrated positive results in two Phase III studies, showing a reduction in disease recurrence and improved survival rates. Mirati's adagrasib, when combined with Keytruda, showed strong first-line promise in NSCLC patients. BeiGene's tislelizumab, in combination with chemotherapy, achieved a major pathological response in a Phase III trial. Johnson & Johnson's Rybrevant-lazertinib combination demonstrated potential as a new standard of care for EGFR-mutated NSCLC. These findings will be presented at the ESMO Congress in October.

Opdivo Combination Therapy Shows Survival Benefit in Metastatic Urothelial Carcinoma
medical2 years ago

Opdivo Combination Therapy Shows Survival Benefit in Metastatic Urothelial Carcinoma

Bristol Myers Squibb has announced positive results from the Phase 3 CheckMate -901 trial, showing that the combination of Opdivo (nivolumab) with cisplatin-based chemotherapy followed by Opdivo monotherapy demonstrated significant benefits in overall survival (OS) and progression-free survival (PFS) compared to standard-of-care cisplatin-based combinations as a first-line treatment for patients with unresectable or metastatic urothelial carcinoma who are eligible for cisplatin-based chemotherapy. This marks the first immunotherapy-based combination to improve both OS and PFS in this patient population, highlighting the potential of Opdivo-based treatments in various genitourinary cancers.