Ohio State vs. Indiana: Predictions, Odds, and How to Watch Week 13 Showdown

The Indiana Hoosiers, ranked No. 5, will face the No. 2 Ohio State Buckeyes in a crucial college football matchup. Ohio State, favored by 10.5 points, has a strong track record against Indiana, winning 21 consecutive meetings. Despite losing star center Seth McLaughlin, Ohio State boasts a potent offense and the nation's best defense. Indiana, with a perfect 10-0 record, has a high-scoring offense and a solid defense, making this a competitive game. SportsLine's model, which has been profitable for bettors, offers predictions for this game.