49ers Face RB Crisis as McCaffrey, Mason Hit IR

TL;DR Summary
The San Francisco 49ers have placed their top two running backs, Christian McCaffrey and Jordan Mason, on injured reserve, paving the way for rookie Isaac Guerendo to start. Guerendo, a fourth-round pick from Louisville, has shown promise with 246 rushing yards and two touchdowns this season. The 49ers, currently at the bottom of the NFC West, hope Guerendo can fill the void as they contend with injuries and aim to improve their 5-7 record.
- 49ers Turn to Rookie Starting RB As Christian McCaffrey, Jordan Mason Head to IR Sports Illustrated
- 49ers RBs McCaffrey, Mason both headed to IR ESPN
- 49ers' Christian McCaffrey suffered 'potentially' season-ending knee injury vs Bills, coach says Fox News
- Christian McCaffrey knee injury update: 49ers RB expected to miss six weeks after being placed on IR CBS Sports
- The financial ramifications of Christian McCaffrey’s injury and what it means for the 49ers future Niners Nation
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