49ers and Rams Prepare for Key NFC West Clash

TL;DR Summary
The San Francisco 49ers' defense will look significantly different in their upcoming game against the Rams due to multiple injuries and lineup changes, which could impact their performance against a strong Rams offense. The 49ers' pass rush has been underwhelming this season, and facing a well-protected Matthew Stafford will be challenging. Additionally, their rushing attack has struggled against top-tier defenses, and the game will be a tough test for their run game against the Rams' solid run defense.
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