Multiple accidents cause lane closures on I-64.

TL;DR Summary
An overturned semitrailer on I-64 W near the I-264 eastbound exit in Louisville has blocked all lanes, and the driver has been seriously injured. The cause of the accident is believed to be speed, according to preliminary investigations by the police. The roadway will remain blocked until the cleanup is complete, and the investigation is ongoing.
- All lanes blocked on I-64 W due to overturned semitrailer, driver 'seriously' injured WLKY Louisville
- Rollover crash on I-64 West seriously injures one person, LMPD says WHAS11.com
- All I-64 eastbound lanes blocked after crash just past Sherman Minton Bridge WLKY Louisville
- Woman seriously injured after semi overturns; all lanes blocked on I-64 West to I-264 East WAVE 3
- TRAFFIC ALERT: Lanes blocked on I-64 West to I-264 East due to overturned semi WAVE 3
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